OCULAR FORMULATIONS FOR DRUG-DELIVERY TO THE POSTERIOR SEGMENT OF THE EYE

摘要

The present invention relates to topical formulations comprising a compound of the following formula:;;for treating ocular neovascularization. The Compound-I is present in a solution or a suspension in about 0.005% to about 5.0% w/v, such that the solution or suspension delivers the compound at the posterior segment of the eye for inhibiting VEGF in the retina and/or the choroid.

主权项

1. A topical ocular formulation, the formulation comprising:
a. an active agent of Formula II: b. or a pharmaceutically acceptable salt thereof, and c. and pharmaceutically acceptable excipients; wherein the active agent or the pharmaceutically acceptable salt is present in about 0.005% to about 5.0% w/v such that the formulation forms a solution or a suspension.