Bispecific heterodimeric diabodies and uses thereof
摘要
Bispecific heterodimeric diabody molecules and uses thereof in the treatment of cancer. The bispecific heterodimeric diabody molecules comprise two polypeptide chains that associate to form two epitope binding sites recognizing the P-cadherin tumor cell associated antigen and the CD3 T cell antigen.
申请公布号
AU2015283704(A1)
申请公布日期
2016.12.15
申请号
AU20150283704
申请日期
2015.06.26
申请人
Pfizer Inc.
发明人
May, Chad Michael;Root, Adam Reid;Brady, William A.;Tchistiakova, Lioudmila Gennadievna;Mosyak, Lidia;Bloom, Laird;Moore, Paul A.;Johnson, Leslie S.