发明名称 Method for cellular RNA expression
摘要 The present invention relates to enhancing RNA expression in a cell such as a cell transfected with RNA by reducing the activity of RNA-dependent protein kinase (PKR). Thus, the present invention provides methods for expressing RNA in a cell comprising the step of reducing the activity of RNA-dependent protein kinase (PKR) in the cell. Reducing the activity of RNA-dependent protein kinase (PKR) in the cell increases the stability of RNA and/or increases the expression of RNA in the cell.
申请公布号 AU2011335428(B2) 申请公布日期 2016.12.22
申请号 AU20110335428 申请日期 2011.12.02
申请人 Universitatsmedizin der Johannes Gutenberg-Universitat Mainz;Translationale Onkologie an der Universitatsmedizin der JGU Mainz GGMBH (TRON);BioNTech AG 发明人 Sahin, Ugur;Beissert, Tim;Poleganov, Marco;Herz, Stephanie
分类号 C12N15/67;C12N5/16 主分类号 C12N15/67
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