BLOOD PRESSURE LOWERING PEPTIDES FROM GLYCOMACROPEPTIDE
摘要
A process to produce IPP from a protein source whereby the protein source comprises a protein having the -I-P-P- sequence and having in the protein amino acid sequence at least 6 times more -I-P-P- present than -V-P-P- (molar basis) which comprises hydrolysing the protein source to liberate at least 40% of the I-P-P- sequence 10 into the peptide IPP and whereby a proteolytic enzyme is used which cleaves at the carboxy-terminus of proline residues present in the protein source, the enzyme is preferably a proline specific endoprotease or proline specific oligopeptidase, more preferably a proline specific endoprotease, and optionally an amino peptidase.
申请公布号
WO2006089921(A1)
申请公布日期
2006.08.31
申请号
WO2006EP60198
申请日期
2006.02.23
申请人
DSM IP ASSETS B.V.;ROOS, DE, ANDRE LEONARDUS;BROECKE, VAN DEN,, PIETER MARINUS;EDENS, LUPPO
发明人
ROOS, DE, ANDRE LEONARDUS;BROECKE, VAN DEN,, PIETER MARINUS;EDENS, LUPPO