| 发明名称 |
Modulators of the glucocorticoid receptor and method |
| 摘要 |
Novel non-steroidal compounds are provided which are glucocorticoid receptor modulators which are useful in treating diseases requiring glucocorticoid receptor agonist or antagonist therapy such as obesity, diabetes, inflammatory and immune disorders, and have the structure where Z is CONR<SUP>1</SUP>R<SUP>2 </SUP>or CH<SUP>2</SUP>NR<SUP>1</SUP>R<SUP>2 </SUP>and where R, R<SUP>a</SUP>, R<SUP>b</SUP>, R<SUP>c</SUP>, R<SUP>d</SUP>, Z, A and B are defined herein.
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| 申请公布号 |
US2005171136(A1) |
申请公布日期 |
2005.08.04 |
| 申请号 |
US20050085347 |
申请日期 |
2005.03.21 |
| 申请人 |
VACCARO WAYNE;YANG BINGWEI V.;KIM SOONG-HOON;HUYNH TRAM;TORTOLANI DAVID R.;LEAVITT KENNETH J.;LI WENYING;DOWEYKO ARTHUR M.;CHEN XIAO-TAO;DOWEYKO LIDIA |
发明人 |
VACCARO WAYNE;YANG BINGWEI V.;KIM SOONG-HOON;HUYNH TRAM;TORTOLANI DAVID R.;LEAVITT KENNETH J.;LI WENYING;DOWEYKO ARTHUR M.;CHEN XIAO-TAO;DOWEYKO LIDIA |
| 分类号 |
A61K31/403;A61K31/415;A61K31/425;A61K31/473;A61K31/495;A61K45/06;C07D207/34;C07D209/48;C07D213/40;C07D213/75;C07D213/82;C07D215/38;C07D217/22;C07D231/16;C07D233/88;C07D235/10;C07D235/14;C07D235/30;C07D239/42;C07D239/94;C07D241/20;C07D261/12;C07D261/14;C07D263/48;C07D277/46;C07D277/64;C07D285/06;C07D307/58;C07D317/58;C07D333/20;C07D333/34;C07D401/04;C07D405/04;C07D417/04;C07D417/10;C07D417/12;C07D471/04;C07D471/08;C07D487/04;C07D495/04;(IPC1-7):C07D471/02;A61K31/474;A61K31/277;A61K31/165;C07C255/60 |
主分类号 |
A61K31/403 |
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