发明名称 IMIDAZOPYRAZINE ANALOGS WITH 3-TERTIARY CARBON SUBSTITUTIONS AS BTK INHIBITORS
摘要 The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts thereof, Formula (I) or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders.
申请公布号 WO2016109220(A1) 申请公布日期 2016.07.07
申请号 WO2015US66225 申请日期 2015.12.17
申请人 MERCK SHARP & DOHME CORP.;LIU, JIAN;KOZLOWSKI, JOSEPH, A.;GAO, XIAOLEI;GUIADEEN, DEODIALSINGH;LIU, SHILAN;WANG, DAHAI 发明人 LIU, JIAN;KOZLOWSKI, JOSEPH, A.;GAO, XIAOLEI;GUIADEEN, DEODIALSINGH;WANG, DAHAI
分类号 A61K31/44;A61K31/4985;A61K31/519 主分类号 A61K31/44
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