发明名称 ANTI-CD14 ANTIBODY-FUSED PROTEIN
摘要 <P>PROBLEM TO BE SOLVED: To provide a novel protein comprising an anti-CD14 antibody and a protease-inhibitory substance, a polynucleotide encoding the novel protein, a method for producing the novel protein, and a preventive and therapeutic agent, etc., for sepsis comprising the novel protein. <P>SOLUTION: Disclosed is a protein comprising (I) an anti-CD14 antibody or an active fragment thereof or a derivative of the antibody or fragment and (II) a substance inhibiting a protease or an active fragment thereof or a derivative of the substance or the fragment. <P>COPYRIGHT: (C)2007,JPO&INPIT
申请公布号 JP2007215546(A) 申请公布日期 2007.08.30
申请号 JP20070076890 申请日期 2007.03.23
申请人 MOCHIDA PHARMACEUT CO LTD 发明人 FURUSAKO MASAJI;NAKAYAMA KAZUYUKI;HOSAKA YOSHITAKA;KAWAHARA TETSUSHI;NAKAMURA MASAKI;TAKEUCHI TAKASHI
分类号 C12N15/09;A61K39/395;A61P9/02;A61P11/00;A61P31/04;C07K14/81;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02 主分类号 C12N15/09
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