| 发明名称 |
MUTANT-SELECTIVE EGFR INHIBITORS AND USES THEREOF |
| 摘要 |
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. |
| 申请公布号 |
US2016332994(A1) |
申请公布日期 |
2016.11.17 |
| 申请号 |
US201615223343 |
申请日期 |
2016.07.29 |
| 申请人 |
Celgene Avilomics Research, Inc. |
发明人 |
Lee Kwangho;Niu Deqiang;Baevsky Matthew Frank |
| 分类号 |
C07D403/12;A61K31/505;C07D239/48;A61K45/06;A61K31/506 |
主分类号 |
C07D403/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: R1 is —CF3 or —Cl; W is —O— or —NH—; R2 is —R or R3 is —R, —C(O)R, or —C(O)OR; and each R is independently C1-4 alkyl or C1-4 fluoroalkyl. |
| 地址 |
Cambridge MA US |
