发明名称 Alfa-form crystal of an acetanilide derivative
摘要 To provide novel crystals useful as an ingredient for the production of a diabetes remedy. The invention is concerned with alpha -form crystal and beta -form crystal of (R)-2-(2-aminothiazol-4-yl)-4'-Ä2-Ä(2-hydroxy-2-phenylethyl)aminoÜethylÜacetanilide. The alpha -form crystal does not exhibit hygroscopicity and has stability such that it can be used as a medicine, and is useful for mass synthesis in the industrial production. The beta -form crystal does not relatively exhibit hygroscopicity and is also useful as a production intermediate of the alpha -form crystal.
申请公布号 HU230481(B1) 申请公布日期 2016.07.28
申请号 HU20040001665 申请日期 2002.10.29
申请人 ASTELLAS PHARMA INC. 发明人 KAWAZOE SOUICHIROU;SAKAMOTO KENICHIROU;AWAMURA YUJI;MARUYAMA TATSUYA;SUZUKI TAKAYUKI;ONDA KENICHI;TAKASU TOSHIYUKI
分类号 C07D277/40;A61K31/426;A61P3/10;C07D277/44 主分类号 C07D277/40
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