发明名称 |
MEVALONATE DIPHOSPHATE DECARBOXYLASE VARIANTS |
摘要 |
Described are mevalonate diphosphate decarboxylase variants having improved activity in converting 3-phosphonoxyisovalerate into isobutene. Such variants can be employed in processes for biologically producing isobutene from 3-hydroxyisovalerate or from 3-hydroxy-3-methylbutyrate into isobutene, for biologically producing isoprenol from mevalonate or from mevalonate-3-phosphate or for biologically producing 1,3-butadiene from 3-hydroxypent-4-enoate or from 3-phosphonoxypent-4-enoate.;Also described is an enzyme which is characterized in that it is capable of converting 3-phosphonoxyisovalerate into isobutene with a kcat of more than 0.1 s−1. |
申请公布号 |
US2016160204(A1) |
申请公布日期 |
2016.06.09 |
申请号 |
US201414903945 |
申请日期 |
2014.07.09 |
申请人 |
GLOBAL BIOENERGIES ;SCIENTIST OF FORTUNE S.A. |
发明人 |
MAZALEYRAT Sabine;DELCOURT Marc;ANISSIMOVA Maria;MARLIERE Philippe |
分类号 |
C12N9/88;C12P7/04;C12P5/02 |
主分类号 |
C12N9/88 |
代理机构 |
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代理人 |
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主权项 |
1. (canceled) |
地址 |
Evry Cedex FR |