发明名称 |
LKB1 gene knockout animals |
摘要 |
A mammal is provided, in which the LKB1 gene can be deleted phase-specifically and tissue-specifically. These mammals are highly useful as tools to reveal the onset mechanism for diseases caused by LKB1 gene deficiency, such as Peutz-Jeghers syndrome and cancers, as well as to develop therapeutic agents, methods, and so on for the diseases.
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申请公布号 |
US2005044584(A1) |
申请公布日期 |
2005.02.24 |
申请号 |
US20040938735 |
申请日期 |
2004.09.10 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA, A JAPANESE CORPORATION |
发明人 |
NEZU JUN-ICHI;OSE ASUKA;JISHAGE KOU-ICHI;JENNE DIETER E. |
分类号 |
C12N9/12;C12N15/85;C12N15/90;(IPC1-7):A01K67/027 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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