发明名称 |
Apparatus and method for circulated flow nuclear magnetic resonance measurement |
摘要 |
The present invention provides an apparatus and a method for performing a nuclear magnetic resonance (NMR) measurement on a sample solution containing small molecules and large molecules such as proteins, and provides an apparatus and a method for repeatedly performing the NMR measurement while stably controlling concentration conditions in a sample and changing a concentration of small molecules. A sample solution containing small molecules and large molecules is circularly transferred between a vessel (10) equipped with a nuclear magnetic resonance probe (24) and a control section (30) in which injection and filtration of small molecules are performed. By transferring the sample solution between them, the NMR measurement can be performed while maintaining a concentration of large molecules to be constant and increasing or reducing a concentration of small molecules so that a concentration ratio of the small molecules relative to the large molecules is changed, the two types of molecules being present in the sample solution. |
申请公布号 |
EP1860452(A1) |
申请公布日期 |
2007.11.28 |
申请号 |
EP20070008344 |
申请日期 |
2007.04.24 |
申请人 |
HITACHI, LTD. |
发明人 |
KITAGAWA, ISAO;OKADA, MICHIYA |
分类号 |
G01R33/30;G01N24/08;G01R33/465 |
主分类号 |
G01R33/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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