| 发明名称 |
Technology for the Preparation of Microparticles |
| 摘要 |
Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful for preparing pharmaceuticals, nutraceuticals, cosmetic products and the like of defined dimensions. |
| 申请公布号 |
US2016235675(A1) |
申请公布日期 |
2016.08.18 |
| 申请号 |
US201615080399 |
申请日期 |
2016.03.24 |
| 申请人 |
Ansun Biopharma, Inc. |
发明人 |
Malakhov Michael P.;Fang Fang |
| 分类号 |
A61K9/16;A61K38/18;A61K38/38;A61K38/48;A61K38/17;A61K38/46;A61K38/42;A61K38/14;A61K31/7036;A61K31/43;C12N15/113;C12N7/00;A61K38/08;A61K38/12;A61K31/65;A61K31/337;A61K31/5575;A61K31/721;A61K31/724;A61K31/198;A61K31/405;A61K38/47 |
主分类号 |
A61K9/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of making microparticles of a compound, comprising:
a) adding a counterion to a solution containing the compound in a solvent; b) adding an antisolvent to the solution; and c) gradually cooling the solution to a temperature below about 25° C., whereby a composition containing microparticles comprising the compound is formed, wherein steps a), b) and c) are performed simultaneously, sequentially, intermittently, or in any order. |
| 地址 |
San Diego CA US |
