THROMBIN RECEPTOR ANTAGONISTS AS PROPHYLAXIS TO COMPLICATIONS FROM CARDIOPULMONARY SURGERY

摘要

Disclosed herein are methods of preventing, inhibiting, or ameliorating complications associated with cardiopulmonary bypass surgery by the use of a thrombin receptor antagonist compound. Among the thrombin receptor antagonis compounds useful in these methods are those of Formulas (I), (II) and (III), described herein. Examples of such thrombin receptor antagonists include formulae (I), (II) and (III).