The present invention provides novel methods for the synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one of formula (III) which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.
申请公布号
ZA200701873(B)
申请公布日期
2008.09.25
申请号
ZA20070001873
申请日期
2007.03.02
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
VEMISHETTI, PURUSHOTHAM;COSTELLLO, CARRIE A.;REIFF, EMILY A.;CHADWICK, SCOTT T.;DESIKAN, SRIDHAR