TRANSLOCATING ENZYME USED AS A SELECTION MARKER

摘要

The invention relates to a system for selecting microorganisms which inactivate essential translocating enzyme and recover said inactivation by an equivalent factor which is made available to respective cells by a vector. The inventive system is adapted, in particular to methods for producing proteins by cell culture of a micro-organism strain which are characterised by said selection system, a respective transgene being situated on a recovery vector. Said invention also relates to respective micro-organisms and to the use of translocating enzyme genes and vectors, in particular the use of