发明名称 Stabilized formulations containing anti-PCSK9 antibodies
摘要 The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human proprotein convertase subtilisin/kexin type 9 (PCSK9). The formulations may contain, in addition to an anti-PCSK9 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.
申请公布号 AU2012286663(B2) 申请公布日期 2016.12.01
申请号 AU20120286663 申请日期 2012.07.27
申请人 Regeneron Pharmaceuticals, Inc. 发明人 Walsh, Scott;Dix, Daniel
分类号 C07K16/40;A61K39/395 主分类号 C07K16/40
代理机构 代理人
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