| 摘要 |
An irradiation device using ionizing radiation, particularly for radiation therapy and/or radiation biology, simultaneously includes: at least one unit (MER) for emitting ionizing radiation; at least one dose-monitoring unit (MCD); at least one unit for detecting an ionizing radiation dose (MDD); and at least one monitoring and control system (SCC). The units (MER, MDD, MCD) and the system (SCC) are also intelligently interconnected therebetween so as to engage with one another and form an intelligent monitoring and adjustment loop, such as to controllably, precisely and desirably produce strong doses of ionizing radiation of at least 0.01 Gy, having a precision within at least one 1 μGy but preferably 1 n Gy, in strong dose rates up to 1000 Gy/s with power within a range of 1 to 50 Me V in very brief time intervals of at least 0.1 μs, preferably 1 ms. |
| 主权项 |
1. An irradiation device using ionizing radiation, in particular for radiotherapy and/or radiobiology, simultaneously comprising at least:
a means for emitting ionizing radiation (MER) comprising:
at least one particle source which comprises at least:
a cathode and an anode, or a plasma,a means for triggering particle emission, in particular a grid or an electrode or a laser anda means for accelerating a particle beam, anda system for power pulse control, an ionizing radiation dose detection means (DDM) comprising a detector, a dose control means (DCM), configured to control the triggering and the stopping of the means for emitting ionizing radiation (MER), comprising:
control electronics (CE),an amplifier and/or an attenuator amplifying and/or attenuating a signal emitted by the detector,an integrator integrating, during the time of the emission, said amplified and/or attenuated signal anda comparator continuously comparing said integrated signal to the settings for the specified dose (SAD) predetermined by an operator, a control and actuating system (CAS) comprising:
a system for functional control (SFC) of the various members of said device, comprising:
a man-machine interface (MMI),viewing tools andimplementation means configured in order for an operator to program, at a single time, the nature of the radiation, the absorbed dose rate of ionizing radiation, a duration for the emission of the ionizing radiation, the pulse settings, wherein: said means (MER, DDM, DCM) and said system (CAS), are configured for delivering and controlling doses of ionizing radiation of at least 0.01 Gy or even 0.25 Gy with an accuracy of at least 1 μGy, preferably 1 nGy, at energies comprised between 1 MeV and 50 MeV, for times comprised between approximately 0.1 μs and 100 ms, preferably 100 μs or 1 ms, the power pulse control system of the means for emitting ionizing radiation (MER) is configured for producing a particle beam, that is to say ionizing radiation, of energy in a range comprised between 1 MeV and 50 MeV, pulsed at a frequency (f) comprised between 5 Hz and 1000 Hz, or even between 5 Hz and 500 Hz, or even between 5 Hz and 200 Hz, and preferably approximately 100 Hz, with a pulse duration (d) of at least 1 ns, preferably comprised between 0.05 μs and 12 μs, preferably 0.1 μs, and for delivering an absorbed dose rate of at least approximately 0.01 Gy/s, for example comprised between approximately 0.01 Gy/s and approximately 250 Gy/s, or even 500 Gy/s or even 1000 Gy/s, the control electronics (CE) of the dose control means (DCM) is configured for controlling a dose delivered for at least 0.1 μs, or even 100 μs, or even 1 ms, or even 100 ms and the detector is an ultra-fast detector, coupled to a dose control means (DCM), configured to detect a dose of ionizing radiation in at least 0.01 ns and at dose rates of at least 0.01 Gy/s, for example 25 Gy/s, or even 50 Gy/s, or even preferably 250 Gy/s, or even 500 Gy/s or even 1000 Gy/s. |
