| 摘要 |
PROBLEM TO BE SOLVED: To provide safe and effective methods of treating, preventing and managing cancer and other diseases and conditions, including diseases that are refractory to standard treatments, such as surgery, radiation therapy, chemotherapy and hormonal therapy, while reducing or avoiding toxicity and/or side effect associated with conventional therapies.SOLUTION: Provided are 4'-arylmethoxy isoindoline compounds represented by the formula in the figure, and pharmaceutically acceptable salts thereof, for treatment of cancer, a disorder associated with angiogenesis, pain, myodegeneration or a related syndrome, a skin disease, a pulmonary disorder, an asbestos-related disorder, a parasitic disease, an immunodeficiency disorder, a CNS disorder, CNS injury, atherosclerosis or a related disorder, dysfunctional sleep or a related disorder, an infectious disease, hemoglobinopathy or a related disorder, or a TNFα related disorder.SELECTED DRAWING: None |
