发明名称 ПРОИЗВОДНЫЕ ИЗОХИНОЛИНА
摘要 Disclosed are isoquinolino derivatives of the formulawherein Y is >C=O or -CH2-, Z is >C=O or -CH2-, and R<1>, R<2 >and m are as defined herein as well as the pharmaceutically acceptable salts thereof. These compounds are MAO-B selective inhibitors useful, inter alia, in the treatment of Alzheimer's disease and/or senile dementia.
申请公布号 RU2004134575(A) 申请公布日期 2005.07.20
申请号 RU20040134575 申请日期 2003.04.14
申请人 Ф.ХОФФМАНН-ЛЯ РОШ АГ (CH) 发明人 Андреа ЦЕСУРА (CH);Роса-Мари  РОДРИГЕС-САРМЬЕНТО (CH);Микельанджело СКАЛОНЕ (CH);Эндрью Уилль м ТОМАС (CH);Рене ВИЛЕР (CH)
分类号 C07D217/04;A61K31/472;A61P25/16;A61P25/28;A61P43/00;C07D217/24;C07D405/06 主分类号 C07D217/04
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