| 摘要 |
Disclosed is a metered dose inhaler containing an aerosol suspension formulation for inhalation comprising: An effective amount of mometasone furoate; An effective amount of formoterol fumarate; and 1,1,1,2,3,3,3-heptafluoropropane (HFA 227); wherein the ratio of mometasone furoate to formoterol fumarate is about 400 micrograms of mometasone furoate to about 12 micrograms of formoterol fumarate to about 50 micrograms of mometasone furoate to about 6 micrograms of formoterol fumarate, wherein the formoterol fumarate flocculates with the mometasone furoate, and wherein the formulation is substantially free of carrier. Metered dose inhalers of the type disclosed are useful in the treatment of allergic and inflammatory reactions in the respiratory tract.
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