| 发明名称 |
PROCESS FOR THE ENZYMATIC SYNTHESIS OF (7S)-1-(3,4-DIMETHOXYBICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-YL) N-METHYL METHANAMINE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND SALTS THEREOF |
| 摘要 |
Process for the enzymatic synthesis of the compound of formula (I), (7S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl) N-methyl methanamine:Application in the synthesis of ivabradine and pharmaceutically acceptable acid addition salts thereof. |
| 申请公布号 |
EA024637(B1) |
申请公布日期 |
2016.10.31 |
| 申请号 |
EA20130000719 |
申请日期 |
2013.07.16 |
| 申请人 |
LES LABORATOIRES SERVIER |
发明人 |
PEDRAGOSA-MOREAU Sandrine;LEFOULON Francois;MORIS VARAS Francisco;GONZALEZ SABIN Javier |
| 分类号 |
C12N9/78;C07C217/58;C07D223/16;C12P13/00 |
主分类号 |
C12N9/78 |
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