摘要 |
1393854 Pharmaceutical preparations containing benzoic acid derivatives PFIZER INC 26 Feb 1973 9443/73 Heading A5B [Also in Division C2] Pharmaceutical preparations suitable for treating atherosclerosis contain (I), (II) and/or (III) and/or salts thereof as active ingredient where X is fluorine, chlorine, bromine, methyl, methoxy or trifluoromethyl; R 1 is methyl, benzyl or substituted benzyl wherein the substituent is fluorine, chlorine, methyl, methoxy, trifluoromethyl or 3, 4-dimethoxy, or acylmethyl of the formula wherein R is alkyl containing from 1 to 4 carbon atoms or phenyl or substituted phenyl wherein the substituent is fluorine, chlorine, methyl, trifluoromethyl or methoxy; R 2 is methyl, 2-hydroxyethyl, allyl, methallyl, crotyl or acylmethyl of the formula wherein R is as defined above and; n is 0, 1 or 2; and R 3 is fluorine, chlorine, bromine or methyl. Administration is orally or parenterally. |