| 发明名称 |
CRYSTALLINE PEPTIDE EPOXY KETONE PROTEASE INHIBITORS AND THE SYNTHESIS OF AMINO ACID KETO-EPOXIDES |
| 摘要 |
The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides. |
| 申请公布号 |
PL2207791(T3) |
申请公布日期 |
2016.10.31 |
| 申请号 |
PL08834964T |
申请日期 |
2008.10.03 |
| 申请人 |
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发明人 |
PHIASIVONGSA PASIT;SEHL LOUIS C.;FULLER WILLIAM DEAN;LAIDIG GUY J. |
| 分类号 |
A61P19/08;A61K38/06;A61P25/28;A61P31/00;A61P33/00;A61P35/00;A61P37/00;A61P37/06;C07D301/00;C07D301/03;C07D303/36;C07K5/087 |
主分类号 |
A61P19/08 |
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