发明名称 SUBSTITUTED AMINOALKYL GUANIDINES
摘要 Compounds corresponding to the formula <IMAGE> I are disclosed, wherein Alk represents a C2-C5-alkylene groups optionally substituted by a hydroxy group and Ar represent an optionally substituted phenyl, naphthyl, tetrahydronaphthyl, indanyl or indenyl radical or a monocyclic or condensed bicyclic or tricyclic heterocyclic radical which is optionally substituted, the heterocyclic radical consisting of individual rings having 5 or 6 members and optionally containing from 1 to 4 hetero atoms, and the acid addition salts thereof. A process for producing these compounds is also disclosed. These substituted aminoalkyl guanidines block the beta -receptors of the adrenergic nerve system, and also reduce blood pressure.
申请公布号 ZA7904662(B) 申请公布日期 1980.08.27
申请号 ZA19790004662 申请日期 1979.09.04
申请人 DEGUSSA 发明人 STROMAN F;KLINGER K;THIEMER K;KLEEMANN A
分类号 A61K31/155;A61K31/403;A61K31/405;A61P25/02;A61P27/02;C07C67/00;C07C239/00;C07C279/04;C07C279/12;C07D209/08;C07D209/43;C07D209/86;C07D209/88 主分类号 A61K31/155
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