| 发明名称 |
Process for chenodeoxycholic acid and intermediates therefore |
| 摘要 |
A multi-step synthesis of chenodeoxycholic acid from 3-keto-bisnorcholenol, a compound readily obtained from the abundant plant sterol beta -sitosterol, is described. A key step in the synthesis is the stereoselective microbial introduction of the 7-alpha hydroxy group into 3-keto-bisnorcholenol.
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| 申请公布号 |
US4230625(A) |
申请公布日期 |
1980.10.28 |
| 申请号 |
US19790029420 |
申请日期 |
1979.04.12 |
| 申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
DESPREAUX, CARL;NARWID, THOMAS A.;PALLERONI, NORBERTO J.;USKOKOVIC, MILAN R. |
| 分类号 |
C07J9/00;C07J31/00;C12P33/06;(IPC1-7):C07J9/00;C07J5/00 |
主分类号 |
C07J9/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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