发明名称 PREPARING PROCESS FOR CYCLIC COMPOUNDS
摘要 5-(Indole-3-yl-methylene)-1,3-dimethyl-2-methyl-imino-4-imidazolidine(I; R = H, lower alkyl), useful for treatment of melancholia, was prepd. by condensation of 1,3-dimethyl-2-methylimino-4-imidazoline and indole-3-aldehyde which was substituted with lower alkyl at 6-position, or by reaction of 5-(indole-3-yl-methylene)-1,3-dimethyl-2-imino-4-imidazolidinone with methylating agent. The compd.(II) is isomer of compd.
申请公布号 KR800001551(B1) 申请公布日期 1980.12.27
申请号 KR19780000525 申请日期 1978.03.02
申请人 HOFFMANN LA ROCHE & CO 发明人 BATCHO A;WELK R;MURPHY P
分类号 A61K31/425;C07D209/10;C07D233/96;(IPC1-7):C07D233/96;A61K31/42 主分类号 A61K31/425
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