摘要 |
5-(Indole-3-yl-methylene)-1,3-dimethyl-2-methyl-imino-4-imidazolidine(I; R = H, lower alkyl), useful for treatment of melancholia, was prepd. by condensation of 1,3-dimethyl-2-methylimino-4-imidazoline and indole-3-aldehyde which was substituted with lower alkyl at 6-position, or by reaction of 5-(indole-3-yl-methylene)-1,3-dimethyl-2-imino-4-imidazolidinone with methylating agent. The compd.(II) is isomer of compd.
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