发明名称 Pharmaceutical compositions for treating or preventing bone conditions
摘要 Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same.
申请公布号 US9511115(B2) 申请公布日期 2016.12.06
申请号 US201012897397 申请日期 2010.10.04
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 Soo Chia;Ting Kang;Kuroda Shunichi;Wu Ben
分类号 C07K14/51;A61K35/32;A61K38/17;A61L27/22 主分类号 C07K14/51
代理机构 Duane Morris LLP 代理人 Duane Morris LLP
主权项 1. A pharmaceutical composition for treating, preventing, or ameliorating a bone related condition in a mammal, comprising an effective amount of a NELL peptide and a carrier or scaffold that includes BMP2 and hyaluronan, wherein the effective amount is effective for a bone related condition selected from the group consisting of osteoporosis, bone loss due to microgravity, disuse atrophy, prolonged bed-rest, and a disease that involves multiple symptoms where bone metabolism is a secondary effect or is selected from the group consisting of atopic soft tissue calcification, gall stone, kidney stones, pineal gland calcification, cataracts, salivary stones, cardiac valves, and prostate stones.
地址 Oakland CA US