发明名称 2-Decarboxy-2-tetrazolyl-4-halo-5,9-epoxy-9-deoxy-PGF1 compounds
摘要 The present invention relates to novel 2-decarboxy-2-tetrazolyl-4-halo-5,9-epoxy-9-deoxy-PGF1 compounds, which are intermediates useful for the preparation of corresponding 5,9 alpha -epoxy-9-deoxy-PGF1 and 5,9-epoxy-9-deoxy-4,5-didehydro-PGF1 compounds. These end products are employed for induction of a variety of prostacyclinlike pharmacological effects. Accordingly, these end products are useful pharmacological agents for the same purposes for which prostacyclin is employed.
申请公布号 US4289888(A) 申请公布日期 1981.09.15
申请号 US19790073456 申请日期 1979.09.07
申请人 THE UPJOHN COMPANY 发明人 JOHNSON, ROY A.
分类号 C07C405/00;C07D307/937;C07D311/94;(IPC1-7):C07D405/02 主分类号 C07C405/00
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