发明名称 Penicillin derivatives, processes for their preparation and compositions containing them.
摘要 <p>A compound offormula (I) or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof: &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="44" wi="75" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein R is phenyl 4-hydroxy phenyl, or a 5- 6- membered heterocyclic ring containing up to three heteroatoms selected from oxygen, sulphur or nitrogen, optionally substituted with hydroxy, amino, halogen or C&lt;Sub&gt;1-6&lt;/Sub&gt; alkoxy; &lt;UnorderedLists id="ula01" listStyle="none"&gt;&lt;ListItem&gt;R&lt;Sup&gt;1&lt;/Sup&gt; represents hydrogen or C&lt;Sub&gt;1-6&lt;/Sub&gt; alkyl;&lt;/ListItem&gt;&lt;ListItem&gt;R&lt;Sup&gt;2&lt;/Sup&gt; and R&lt;Sup&gt;3&lt;/Sup&gt; are the same or different and represent hydrogen, C&lt;Sub&gt;1-6&lt;/Sub&gt;alkyl, halogen, amino, hydroxy, or C&lt;Sub&gt;1-6&lt;/Sub&gt; alkoxy.&lt;/ListItem&gt;&lt;/UnorderedLists&gt;</p><p>Their preparation and use is described.</p>
申请公布号 EP0041813(A1) 申请公布日期 1981.12.16
申请号 EP19810302424 申请日期 1981.06.02
申请人 BEECHAM GROUP PLC 发明人 BENTLEY, PETER HUBERT;HARDY, KENNETH DAVID;MILNER, PETER HENRY
分类号 A61P31/04;C07D499/12;A61K31/43;C07D499/00;C07D499/04;C07D499/21;C07D499/64;C07D499/68;C07D499/70;(IPC1-7):07D499/00;61K31/43 主分类号 A61P31/04
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