FREMGANGSMAATE FOR FREMSTILLING AV 3-(HYDROKSY-1,2,4-TRIAZINYL)TIOMETYL-CEFALOSPORINER

摘要

Cephalosporin derivatives effective against gram-negative bacteria and virtually inactive against staphylococci are disclosed. The derivatives have the following general formula: in which R is R'' and R''' are hydrogen, lower alkyl or together are 1,3-propylene or 1,4-butylene, and X and X' are hydrogen, cation or easily metabolically labile and pharmaceutically acceptable ester or hemiacetal.