发明名称 METHODS FOR TREATING HEMATOLOGICAL MALIGNANCIES
摘要 Described herein are methods for treating hematological malignancies and/or solid tumors in a subject using inhibitors of integrin alpha 6. In some embodiments, the inhibitors are monoclonal antibodies. The antibodies may be conjugated to additional therapeutic agents. The antibodies may be co-administered sequentially or simultaneously with additional therapeutic agents.
申请公布号 US2016280789(A1) 申请公布日期 2016.09.29
申请号 US201415033879 申请日期 2014.11.10
申请人 CHILDREN'S HOSPITAL LOS ANGELES ;FRED HUTCHINSON CANCER RESEARCH CENTER 发明人 Kim Yong-mi;Wayner Elizabeth
分类号 C07K16/28;A61K47/48;A61K39/395;A61K45/06 主分类号 C07K16/28
代理机构 代理人
主权项 1. A method for treating a hematological malignancy in a subject in need thereof comprising: (a) providing a composition comprising an inhibitor of integrin alpha 6; (b) administering an effective amount of the inhibitor so as to treat cancer in the subject.
地址 Los Angeles CA US