发明名称 |
METHODS FOR TREATING HEMATOLOGICAL MALIGNANCIES |
摘要 |
Described herein are methods for treating hematological malignancies and/or solid tumors in a subject using inhibitors of integrin alpha 6. In some embodiments, the inhibitors are monoclonal antibodies. The antibodies may be conjugated to additional therapeutic agents. The antibodies may be co-administered sequentially or simultaneously with additional therapeutic agents. |
申请公布号 |
US2016280789(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
US201415033879 |
申请日期 |
2014.11.10 |
申请人 |
CHILDREN'S HOSPITAL LOS ANGELES ;FRED HUTCHINSON CANCER RESEARCH CENTER |
发明人 |
Kim Yong-mi;Wayner Elizabeth |
分类号 |
C07K16/28;A61K47/48;A61K39/395;A61K45/06 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating a hematological malignancy in a subject in need thereof comprising:
(a) providing a composition comprising an inhibitor of integrin alpha 6; (b) administering an effective amount of the inhibitor so as to treat cancer in the subject. |
地址 |
Los Angeles CA US |