发明名称 CINNAMIC ACID DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 A compound of the formula (I): <IMAGE> (I) <IMAGE> or a pharmaceutically acceptable ester, amide or salt thereof wherein R1 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methylsulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R2 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl group; R3 is a hydrogen, chlorine or bromine atom or a hydroxyl group; R4 is a hydrogen, chlorine or fluorine atom or a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R5 is a hydrogen atom or a methyl group; R6 is a hydrogen atom or a methyl group; R7 is a hydrogen atom or a methyl or ethyl group; R8 is a hydrogen atom or a methyl or ethyl group; X is an oxygen atom or a bond, and Y is an alkylene group of up to 5 carbon atoms, or a bond has been found to possess anti-obesity and/or anti-hyperglycaemic activity.
申请公布号 DE3062216(D1) 申请公布日期 1983.04.07
申请号 DE19803062216 申请日期 1980.09.01
申请人 BEECHAM GROUP PLC 发明人 AINSWORTH, ANTHONY TREVOR;SMITH, DAVID GLYNN
分类号 C07C205/56;C07D317/26;(IPC1-7):07C101/28;07C103/28;07C103/76;61K31/165;61K31/195 主分类号 C07C205/56
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