| 摘要 |
<p>Capped oligonucleotide anti-viral agent comprising: a cap having the formula m<7>G (5 min )-ppp (5 min ) Nm, where N=A or G and m=2 min O-methyl ribose, a linkage group X, attached to said cap, where X=A, G, C or U, a polymeric chain attached to said linkage group comprised of nucleotides that inhibit influenza virus RNA transcription when in polymer form, said polymeric chain being modified to prevent it from acting as a primer to stimulate transcription.</p> |
