发明名称 Spasmolytically active (+)S-enantiomer of secoverine.
摘要 <p>The invention concerns spasmolytically active pharmaceutical compositions, and the preparation thereof, containing (+) S-1-cyclohexyl-4-[ethyl-(p-methoxy- alpha -methylphenethyl)amino]-1-butanone or a salt thereof as the active component. It has been found that this (+) S-enantiomer is about twice as active as the racemate (which is known as secoverine). This better activity is not related with a proportional increase of undesired side-effects.</p>
申请公布号 EP0100569(A1) 申请公布日期 1984.02.15
申请号 EP19830200987 申请日期 1983.07.04
申请人 DUPHAR INTERNATIONAL RESEARCH B.V 发明人 HARTOG, JAN;ZWAGEMAKERS, JOHANNES MARIA ANTONIUS;VAN WIJNGAARDEN, INEKE
分类号 A61K31/135;C07C67/00;C07C213/00;C07C225/10;(IPC1-7):07C97/065;61K31/135 主分类号 A61K31/135
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