发明名称 |
Spasmolytically active (+)S-enantiomer of secoverine. |
摘要 |
<p>The invention concerns spasmolytically active pharmaceutical compositions, and the preparation thereof, containing (+) S-1-cyclohexyl-4-[ethyl-(p-methoxy- alpha -methylphenethyl)amino]-1-butanone or a salt thereof as the active component. It has been found that this (+) S-enantiomer is about twice as active as the racemate (which is known as secoverine). This better activity is not related with a proportional increase of undesired side-effects.</p> |
申请公布号 |
EP0100569(A1) |
申请公布日期 |
1984.02.15 |
申请号 |
EP19830200987 |
申请日期 |
1983.07.04 |
申请人 |
DUPHAR INTERNATIONAL RESEARCH B.V |
发明人 |
HARTOG, JAN;ZWAGEMAKERS, JOHANNES MARIA ANTONIUS;VAN WIJNGAARDEN, INEKE |
分类号 |
A61K31/135;C07C67/00;C07C213/00;C07C225/10;(IPC1-7):07C97/065;61K31/135 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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