Peptides, process for preparing the same and psychodepressant compositions containing the same.

摘要

This invention provides a peptide represented by the formula R-Tyr(SO<Sub>3</Sub>H)-Met-Gly-Trp-Met-Asp-W-NH<Sub>2</Sub> wherein R is HOOC-A-CO-Asp- (wherein A is lower alkylene), pGlu-Asp-, HOOC-A-CO (wherein A is lower alkylene) or
<Chemistry id="chema01" num="0001"><Image id="ia01" he="10" wi="33" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>and W is Phe or N"-lower alkyl-Phe, or a salt thereof, process for preparing the peptide and psychodepressant composition containing the peptide.

The peptides of the invention are useful as psychodepressant drug, and especially effective for curing schizophrenia.