发明名称 Process for producing interferon inducers
摘要 A process for producing interferon inducers from the plants, comprising extracting a water-soluble interferon inducer with water from the tissue of a plant selected from the genera Atractylodes, Lonicera, Plantago, Lithospermum, Ligusticum, Cnidium, Bupleurum, Notopeterygium, Heracleum, Aralia, Panax, Polygala, Sophora, Euchresta, Astragalus, Sinomenium, Stephania, Cocculus, Cimicifuga, Rheum, Gastroida, Asparagus, Pinellia, Evoida and variants thereof capable of producing said interferon inducer at a temperature of from ambient to the boiling point of the extraction mixture for a period sufficient to extract the major portion of said interferon inducer present in the plant tissue, forming a supernatant, fractionating the supernatant to yield fractions containing the major portion of said interferon inducer in the supernatant and recovering said interferon inducer therefrom. Preferably, the fractionation may be effected by ultrafiltration. The interferon inducers thus obtained have a molecular weight of from about 30,000 to about 3,000,000 and are of potential interest for preventing and treating various diseases of humans and animals caused by viral infection.
申请公布号 US4469685(A) 申请公布日期 1984.09.04
申请号 US19830491844 申请日期 1983.05.05
申请人 THE KITASATO INSTITUTE 发明人 KOJIMA, YASUHIKO;KONNO, SEISHI;TAMAMURA, SADAO;HASHIMOTO, TAKASHI
分类号 (IPC1-7):A61K35/78 主分类号 (IPC1-7):A61K35/78
代理机构 代理人
主权项
地址