发明名称 CHIRAL ACID ESTERS
摘要 <p>A process for the preparation of an ester of chiral (A) acid with an optically active (S) alpha -cyano-3-phenoxybenzyl alcohol by reacting an ester of chiral (A) acid with alpha -cyano-3-phenoxybenzyl alcohol of the formula <IMAGE> B in its optically active (R) form or a racemic (R,S) mixture or a mixture of esters of said (R) alcohol and (S) alcohol in non-equimolecular proportions designated herein as "ester (R+S)" with a base selected from the group consisting of ammonium hydroxide, primary, secondary and tertiary amines, quaternary ammonium compounds, liquid amines of high molecular weight, ion exchange resins of a basic character and a catalytic amount of a strong base in at least one solvent in which the ester of the (R) alcohol is soluble and in which the ester of the (S) alcohol is insoluble and recovering from the resulting medium the chiral (A) acid ester of the (S) alcohol which is insoluble.</p>
申请公布号 SG23184(G) 申请公布日期 1985.01.04
申请号 SG19840000231 申请日期 1984.03.12
申请人 ROUSSEL UCLAF 发明人
分类号 A01N37/34;A01N53/00;A01N53/08;A01N53/14;A01P7/04;A61K31/545;C07B31/00;C07B55/00;C07B57/00;C07C67/00;C07C69/74;C07C69/743;C07C253/00;C07C253/30;C07C255/32;C07C255/38;C07C255/39;C07C255/53;C07D501/06;(IPC1-7):C07C121/75 主分类号 A01N37/34
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