| 摘要 |
PURPOSE:To obtain isocarbostyril pharmaceutical preparation having a little change with time, obtained by using an isocarbostyril compound useful as a remedy for heart diseases and a stabilizer such as magnesium silicate, magnesium oxide, etc. CONSTITUTION:4-( 3-Tertiary butylamino-2-hydroxy )propoxy-2-methyl-isocarbostyril hydrochloride (active component for short) is used with at last one stabilizer selected from magnesium silicate, magnesium oxide, hydrotalcite, and NaHCO3. An amount of the stabilizer is 1-3 times as much as the active component by weight. The use of the stabilizer provides the titled pharmaceutical preparation having low reduction in content of the active component, and a little change of properties such as browning with time.
|
