| 摘要 |
NEW MATERIAL:The naphthalene and naphthoquinone derivative of formula I (ring A is group of formula II or formula III; R1 is lower alkyl; R2 is H, 1-20C alkyl, lower phenylalkyl, allyl or 1-10C alkyl having benzyloxy or OH group as a sustituent group; when the ring A is the group of formula III, R2 is not H). EXAMPLE:2-(1-Hydroxyethyl)-4,5,8-tetramethoxynaphthalene. USE:The compound has anti-inflammatory, anticomplementary, hypotensive, cardiopathy-remedying, antiallergicm platelet coagulation inhibiting and antitumor activities, etc, and is useful as an anti-inflammatory and analgestic agent, hipotensor,remedy for cardiopathy, antiallergic agent, antithrombic agent, antitumor agent, antibacterial agent, etc. PREPARATION:The compound of formula V which is one of the compound of formula I can be produced by the Gringnard reaction of the compound of formulaV (R2' is 1-20C alkyl, etc.).
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