发明名称 TRITERPENE ALCOHOL ORGANIC ACID ESTER AND PRODUCTION THEREOF
摘要 NEW MATERIAL:An alpha-1-4C alkyl cinnamate having one or two substituent groups of triterpene alcohol on the benzene nucleus, or a benzoic acid ester or cinnamic acid ester having two substituent groups comprising 1-4C alkoxy group and nitro group, amino group, acylamino group, etc., on the benzene nucleus. EXAMPLE:Cycloartenol-3-methoxy-4-propionyloxy-alpha-methyl cinnamate. USE:Antihyperlipemia. PREPARATION:The objective triterpene alcohol organic acid ester can be produced e.g. by reacting (A) triterpene alcohol with (B) acid halogenide of (i) an alpha-1-4C alkylcinnamic acid having one or two substituent groups on the benzene nucleus or (ii) a benzoic acid or cinnamic acid having two substituent groups comprising 1-4C alkoxy group and nitro group, amino group, or acylamino group, etc., on the benzene nucleus.
申请公布号 JPS61243099(A) 申请公布日期 1986.10.29
申请号 JP19850085254 申请日期 1985.04.19
申请人 AMANO PHARMACEUT CO LTD 发明人 KIMURA GORO;HIROSE YOSHIHIKO;YOSHIDA HISAMI
分类号 A61K31/575;A61P3/06;C07J9/00;C07J53/00 主分类号 A61K31/575
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