| 摘要 |
PURPOSE:An antitumor agent that contains, as an active ingredient, 3-(3-methyl-2- butenyl)-4-hydroxybenzoic acid which is easily derived from the basic skeleton of a component in a Chinese medicine, Artemisia capillaris, thus having a strong antitumor action as well as cholagogue action. CONSTITUTION:The objective antitumor agent is obtained by using 3-(3-methyl-2- butenyl)-4-hydroxybenzoic acid of formula I as an active ingredient. The compound of formula I manifests its antitumor action by oral administration. Further, it promotes the secretion of bile and efficacious for hepatitis caused by carbon tetrachloride or ethanol. The compound of formula I is easily synthesized from 4-hydroxybenzoic acid of formula II.
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