| 摘要 |
NEW MATERIAL:A compound expressed by formula I (ring A is benzopyran ring, tetrahydroquinoline ring or indoline ring; which may have a substituent group; R is phenyl or pyridyl which may have a substituent group; n is 0 or 1 or an acid addition salt thereof. EXAMPLE:2-[(3-Methyl-2-pyridyl)methylthio]pyrano[3,2-e]benzimidazole. USE:An antiulcer agent, analgesic agent and anti-inflammatory agent. PREPARATION:A compound expressed by formula II is reacted with a compound expressed by formula III (X is halogen) in the presence of a base, e.g. NaHCO3, NaOH or pyridine, in a solvent, e.g. benzene, methanol, DMF or waster, at 60-110 deg.C for 20min-6hr to afford the aimed compound expressed by formula I etc.
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