GLUCOSYLMORANOLINE DERIVATIVE

摘要

NEW MATERIAL:The compound of formula (R is hydrocarbon group having hydroxyl group). EXAMPLE:4-O-alpha-D-glucopyranosyl-N-(2-hydroxyethyl) moranoline. USE:A remedy for diabetes active to suppress the increase of blood sugar level. PREPARATION:The objective derivative can be produced e.g. by reacting 4-O-D- glucopyranosylmoranoline with an epoxide (e.g. epibromohydrin) in a solvent such as dimethyl sulfoxide in the presence of potassium carbonate, etc., e.g. at 100-110 deg.C for 3 hr.