| 摘要 |
PURPOSE:To obtain a polysaccharide derivative excellent in solvent resistance and suitable as a reagent for optical resolution, by bonding part of the hydroxyl groups of a polysaccharide to silica gel and introducing substituents into the rest of the hydroxyl groups. CONSTITUTION:Part of the hydroxyl groups of a polysaccharide are chemically bonded to silane-treated silica gel through a polyfunctional isocyanate derivative. Substituents are introduced into the rest of the hydroxyl groups. As the polysaccharides, cellulose, amylose, beta-1,4-chitosan, chitin, beta-1,4-mannan, inulin, etc., which can be easily obtained in the form of highly pure polysaccharide are desirable. As said polyfunctional isocyanate derivatives, any of aliphatic and aromatic ones can be used, and especially, a diisocyanate is desirable. Examples of the compounds having functional groups which are introduced into the rest of the hydroxyl groups of a polysaccharide include isocyanic acid derivatives, carboxylic acids, esters, acid halides, acid amides, aldehydes, and alcohols.
|
