| 摘要 |
PURPOSE:To obtain antitumor agent showing extremely excellent antitumor action, extremely low toxicity, containing a 8-substituted cordycepin or an acid addition salt thereof as an active ingredient. CONSTITUTION:A 8-substituted cordycepin shown by the formula [R is NR1R2 (R1 and R2 are H or 1-7C alkyl), azido or halogen] or a physiologically acceptable acid addition salt alone is pharmaceutically manufactured or blended with an ordinary drug carrier and pharmaceutically manufactured by a conventional procedure to give the aimed substance. A dose is 20-4,000mg, preferably 100-1,000mg per adult daily. The compound shown by the formula, for example, is obtained by treating cordycepin with a bromine solution or a halogenating agent.
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