| 发明名称 |
Inhibitor of ribonucleotide reductase. |
| 摘要 |
<p>The pentapeptide Val Val Asn Asp Leu has been found to be the shortest peptide sequence that inhibits the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication. Longer peptides also have been found that are effective inhibitors.</p> |
| 申请公布号 |
EP0292255(A2) |
申请公布日期 |
1988.11.23 |
| 申请号 |
EP19880304490 |
申请日期 |
1988.05.18 |
| 申请人 |
MERCK & CO. INC. |
发明人 |
FREIDINGER, ROGER;HANNAH, JOHN;COLONNO, RICHARD;STEIN, ROBERT B.;GARSKY, VICTOR M.;TOLMAN, RICHARD |
| 分类号 |
A61K38/55;A61K38/00;A61P31/12;C07K7/06;C07K7/08;C07K14/00;C07K14/035;C12N9/99 |
主分类号 |
A61K38/55 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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