发明名称 PHARMACEUTICAL PREPARATION FOR TREATING AIDS VIRUS INFECTION
摘要 PURPOSE:To obtain a preparation for treating AIDS virus infections, by adding organogermanium sesquioxide, thus having immunization accelerating and controlling action to increase host protection. CONSTITUTION:The object preparation is obtained by using an organogermanium sesquioxide of the formula [R1-R3 are H, lower alkyl, phenyl; X is -OH, -Metal (Na or K), -NH2, -O-alkyl] in a usual manner. It can be given orally or parenterally such as intramuscularly or intravenously and the dose is 1,000-6,000 mg/day. The compound of the formula is obtained by allowing germanium trichloride to react with acrylonitrile, hydrolyzing the product into carboxyethyltrichlorogermanium, treating the compound with thionyl chloride followed by hydrolysis to give the compound of the formula where X is -OH.
申请公布号 JPS63307821(A) 申请公布日期 1988.12.15
申请号 JP19880130469 申请日期 1988.05.30
申请人 ASAI GERUMANIUMU KENKYUSHO:KK 发明人 KAKIMOTO NORIHIRO;KOBAYASHI HIROYUKI;ASO HISASHI;ONISHI TSUTOMU
分类号 A61K31/28;A61P31/12;A61P31/18;A61P37/04;C07F7/30 主分类号 A61K31/28
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