| 摘要 |
<p>A process and apparatus are disclosed for quantitating chromatographic information. The method uses a discrete, linear, translation invariant filter function a @ , where N is a measure of the filter function width and alpha is a parameter whose value determines signal to noise characteristics of the filter function. First a chromatographic analysis of a sample is performed to obtain a first chromatogram. Then the first chromatogram is filtered with the filter function, with N set to approximate the width of peaks obtained in the first chromatogram, and alpha is set to filter out high frequency noise from the first chromatogram to obtain a second chromatogram having a first filtered baseline. The second chromatogram is then filtered with alpha set to resolution enhance peaks in the second chromatogram to obtain a third chromatogram having a baseline which is substantially the same as the first filtered baseline. The second chromatogram is then subtracted from the third chromatogram to obtain a fourth chromatogram which is baseline corrected.</p> |
