发明名称 New enantiomers and their isolation.
摘要 The novel (+)-enantiomer of 1-(3-dimethylaminopropyl)-1-(4 min -fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile as well as acid addition salts thereof are described as valuable antidepressants, geriatrics or in the treatment of obesity and alcoholism. Novel intermediates and a method for the preparation of the (+)-enentiomer as well as the racemic mixture are described.
申请公布号 EP0347066(A1) 申请公布日期 1989.12.20
申请号 EP19890305532 申请日期 1989.06.01
申请人 H. LUNDBECK A/S 发明人 BOEGESOE, KLAUS PETER;PERREGAARD, JENS
分类号 A61K31/00;A61K31/34;A61K31/343;A61P3/00;A61P3/04;A61P25/24;A61P25/26;A61P25/30;C07B57/00;C07C;C07C255/00;C07C255/54;C07C255/58;C07C255/59;C07C303/00;C07C309/00;C07D;C07D307/00;C07D307/78;C07D307/84;C07D307/87 主分类号 A61K31/00
代理机构 代理人
主权项
地址